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Freezing Point Osmometer

Product Information Product code : OSM100100

Freezing Point Osmometer is designed for routine medical, research, and industry measurements that determine the total osmolality of aqueous solutions. It is easily controlled via an intuitive touch screen display. The built-in printer and data saving capability streamline workflow and promote seamless data management.

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Osmolality Measurement

OSM100100 Osmometer measures the total osmolality of any aqueous solution, using Freezing Point Depression method.Osmolality of a solution is the number (or amount of substance) of the osmotically active particles (eg. Salt ions, urea, proteins) present per kilogram of solvent (water). The freezing point of a solvent is depressed by adding solute or mixable substances. Whereas water has a freezing point of 0°C, an aqueous solution with an osmotically active particle concentration of 1 Osm/kg has a freezing point of -1.858°C.

Fast Cooling

Intuitive touch screen

Data storage

  • Specifications
  • Features
  • Downloads
Model OSM100100
Single or Batch Single
Throughput 1 sample
Calibration Point 2 or more points
Sample Volume required 60μl
Range 0~3000 mOsm/kg
Accuracy ±2 mOsm /kg ( ≤ 400 mOsm /kg); ±1.0% ( > 400 mOsm /kg)
Test time < 2min 30sec/run
Connectivity Built-in printer; RS232
Consumables Four E’s 0.5ml sample tube or Axygen PCR-05-C
Dimension 23cm×21cm×36 cm


  • Built-in large touch screen for intuitive operation of the instrument

  • High-precision sensor guarantees accurate measurements & repeatability

  • Dual refrigeration system for faster cooling and continuous testing

  • Small sample quantity requirement for testing

  • Molar concentration, freezing point, molar concentration ratio measured

  • Multipoint calibration (2 or more points) with any standard concentration

  • Refrigerant-free cooling and therefore less maintenance requirement

  • Micro-computer controller can automatically process and store data

  • Built-in printer with multiple printing format settings.

OSM100100 Osmometer User Manual


Osmometers are used in a broad spectrum of laboratory applications: 1. Clinical chemistry: for testing whole blood, serum, plasma, urine and other body fluids for metabolic and electrolytic disorders and intoxication 2. Pharmaceutical industry: bioprocess monitoring at critical points during manufacturing 3. Organic and inorganic chemistry: to determine the average molecular weight of polymers or other unknown compounds or mixtures 4. Other biology applications: analysis of plant saps, hydroponic or cell culture media

4E’S Vs Other Brands

Touch screen display

Built-in printer

Fast cooling function

Two Year Warranty

Frequently Asked Questions

Everything you need to know about product and billing. Can’t find the answer you are looking for? Please write your question to us at

Does the unit have built in printer?

Yes, the unit has a built-in printer.

What is the warranty on the item?

Four E's Equipment comes with a two year all-inclusive warranty.

Do you stock this item?

Yes, this item is in stock at our NJ warehouse.